To improve the solubility of polyacrylamide, you can try the following methods:

1. Increase Temperature: Polyacrylamide generally has better solubility at higher temperatures. Therefore, heating the solvent or solution can help enhance the solubility. Be sure to check the maximum temperature limit for polyacrylamide, as excessive heat can degrade the polymer.

2. Use Cosolvents: Cosolvents are substances that can be added to the solvent or solution to enhance the solubility of the polymer. Commonly used cosolvents for polyacrylamide include alcohols (e.g., ethanol, isopropanol), dimethyl sulfoxide (DMSO), or nitriles (e.g., acetonitrile). Experiment with different cosolvents and their concentrations to find the optimum conditions for solubility.

3. Adjust PH: The solubility of polyacrylamide can be affected by the pH of the solution. Generally, polyacrylamide has better solubility in alkaline conditions. Adjusting the pH of the solvent or solution using a base, such as sodium hydroxide (NaOH), can potentially improve solubility.

4. Increase Mixing or Stirring: Agitating the solvent or solution by increasing mixing or stirring can help improve the solubility of polyacrylamide. This enhances the contact between the polymer and the solvent, aiding in dissolution.

5. Pre-dissolve Polyacrylamide: If you are experiencing difficulty in dissolving polyacrylamide directly in the solvent, you can try pre-dissolving it in a small amount of water before adding it to the main solvent. This can help to disperse the polymer more evenly and improve its solubility.

6. Use Water-Soluble Polyacrylamide Derivatives: Alternatively, you can consider using water-soluble derivatives of polyacrylamide, such as polyacrylamide copolymers or modified polyacrylamide derivatives. These derivatives are designed to have improved solubility in water or other solvents compared to pure polyacrylamide.

Remember, it is always recommended to perform small-scale trials and test different methods to find the best conditions for enhancing the solubility of polyacrylamide for your specific application.